If I were to try this out in a list it would have to be some Mana Denial strategy with strips/wastes, maybe spheres of some form or another. The idea being that this will continue to mill (exile) all Moxen/Lands it hit's until it hits the CMC requirement. No you may not hit that key combo card, but you are likely to hit 5+ mana sources. Throw in spheres/Thalia's, wastelands, Revokers, Null Rods, Ouphes, etc etc, you can easily mana screw any current list. Just my thought on it.